Cancer Care: Areas of Expertise
Prostate Cancer: Management
of Prostate Cancer— An Overview of Approaches
There are a wide variety of treatments available
for the management of prostate cancer. Radical prostatectomy, external
beam radiation, and radioactive prostate seed implant are potential
cures for prostate cancer. Hormone therapy may force the cancer
into a prolonged remission but does not provide a cure unless
it is combined with other treatments. The most commonly used treatments
include the following:
- RADICAL PROSTATECTOMY—surgical
removal of the entire prostate gland.
- EXTERNAL BEAM RADIATION—treatment
with high energy X-rays, delivered by powerful linear accelerators.
The X-rays pass through the patient and preferentially kill cancer
cells.
- RADIOACTIVE PROSTATE SEED
IMPLANT—treatment delivered by radioactive
pellets that are placed directly into the prostate and surrounding
tissues. This type of treatment is also called brachytherapy, which
comes from the Greek word “brachy” which means near or
close to; in other words, therapy that is near or close to the tumor.
The two types of radioactive seeds most commonly used are: Palladium-103
(Pd-103) and Iodine-125 (I-125). Seed implants can deliver two to four
times more radiation than external beam radiation.
- HORMONE THERAPY—treatment
which either stops male hormone production or blocks male hormones
from acting on the tumor. Most prostate cancers are stimulated
to grow by testosterone and other similar male hormones. When the
production of these hormones is suppressed, or these hormones are
prevented from getting to the tumor, the cancer will usually stop
growing and shrink. This treatment can work well for many years.
- WATCHFUL WAITING—patients
whose cancers are not likely to harm them are candidates for watchful
waiting. With watchful waiting, patients do not undergo treatment,
but rather they are carefully monitored with routine PSA tests.
For some patients periodic repeat prostate biopsies are also performed.
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