A blood test will show high levels of amylase. However, macroamylasemia can look similar to acute pancreatitis, which also causes high levels of amylase in the blood.
Measuring amylase levels in the urine can help tell macroamylasemia apart from acute pancreatitis. Urine levels of amylase are low in people with macroamylasemia, but high in patients with acute pancreatitis.
Todd Eisner, MD, Private practice specializing in Gastroenterology, Boca Raton, FL. Affiliate Assistant Professor, Florida Atlantic University School of Medicine. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.