Genetic testing is available for most forms of the disease.
There is no known cure. Orthopedic surgery or equipment (such as braces or orthopedic shoes) may make it easier to walk.
Physical and occupational therapy may help maintain muscle strength and improve independent functioning.
Charcot-Marie-Tooth disease slowly gets worse. Some parts of the body may become numb, and pain can range from mild to severe. Eventually the disease may cause disability.
Progressive inability to walk
Injury to areas of the body that have decreased sensation
When to Contact a Medical Professional
Call for an appointment with your health care provider if there is persistent weakness or decreased sensation in the feet or legs.
Genetic counseling and testing is advised if there is a strong family history of the disorder.
Sarnat HB. Hereditary motor-sensory neuropathies. In: Kliegman RM, Stanton BF, St. Geme III JW, Shor NF, Behrman RE, eds. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 605.
Chad Haldeman-Englert, MD, FACMG, Wake Forest School of Medicine, Department of Pediatrics, Section on Medical Genetics, Winston-Salem, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.